Idiopathic Scrotal Calcinosis: Sonographic Hallmarks.

Idiopathic scrotal calcinosis (ISC) is a rare, benign dermatological condition consisting of deposits of calcium within the scrotal skin. On examination, ISC is characterized by painless, firm nodules and papules localized to the scrotal skin. Typically presenting in adolescence or early adulthood, ISC is more prevalent in males aged 20 to 40, though cases have been reported across all age groups. The lesions initially match the skin tone but may become yellowish and lobulated, sometimes discharging a chalky white substance. Despite its unclear etiology, ISC is hypothesized to arise either idiopathically or through calcification of preexisting dermal structures. More recently, some researchers have suggested that degeneration of the dartos muscle may play a role in the pathogenesis of ISC, like the process of calcification in uterine fibroids. Imaging, particularly ultrasound, plays a pivotal role in diagnosis by identifying hyperechoic, avascular nodules within the scrotal dermis. These can be further characterized by computed tomography and magnetic resonance imaging, however, not usually required. Histopathologic examination remains the gold standard for definitive diagnosis postexcision. Surgical removal is the only effective treatment and is usually performed for cosmetic purposes. Awareness of ISC's imaging features is essential for accurate diagnosis and management.

Copyright © 2025 Wolters Kluwer Health, Inc. All rights reserved.