Planetary Health Diet and risk of mortality and chronic diseases: Results from US NHANES, UK Biobank, and a meta-analysis.

Yuanyuan Wang, Da Pan, Chen Zhang, Dengfeng Xu, Yifei Lu, Shiyu Yin, Pei Wang, Jiayue Xia, Junhui Yu, Lirong Dong, Guiju Sun

Journal: Science advances 2025;11(36):eadq5147

PMID: 40911663

Abstract

The health benefits of the Planetary Health Diet (PHD) require further validation. We examined associations between PHD adherence and risks of mortality and chronic diseases using data from two prospective cohorts-the US NHANES (1999-2018, 42,947 participants) and the UKB (125,372 participants)-and a meta-analysis of 37 published cohort studies (3,244,263 participants). Higher adherence to PHD was associated with lower all-cause mortality in both cohorts. In the UKB, it was also associated with reduced the risk of cancer and respiratory disease mortality. In the meta-analysis, higher adherence to the PHD was associated with lower risks of all-cause, cancer, and cardiovascular disease (CVD) mortality and reduced risks of colorectal cancer, lung cancer, CVDs, coronary heart disease, stroke, and diabetes. This analysis suggests that higher adherence to the PHD may offer substantial health benefits.

Address: Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, and Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, and Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing 210009, China.; Institute of Food and Nutrition Development, Ministry of Agriculture and Rural Affairs, Beijing 100081, China.; Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
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