Potential Biomarkers and Treatment of Neuroinflammation in Parkinson's Disease.

Ziqi Zhao, Ge Yang, Qiang Fu, Xiangyu Guo, Huihan He

Journal: Actas espanolas de psiquiatria 2025;53(1):181-188

PMID: 39801407

Abstract

Parkinson's disease (PD) is a degenerative disease of the central nervous system primarily affecting middle-aged and elderly individuals, significantly compromising their quality of life. Neuroinflammation is now recognized as a key feature in the pathogenesis of PD. This study reviews recent advances in the identification of potential biomarkers associated with neuroinflammation in PD and their significance for therapeutic strategies. These findings suggest that inflammatory factors play a pivotal role in PD treatment, and interventions involving anti-inflammatory drugs, physical exercise, and dietary modifications have shown promising results in mitigating disease progression.

Address: College of Traditional Chinese Medicine, Changchun University of Traditional Chinese Medicine, 130117 Changchun, Jilin, China.; Department of Geriatrics, Affiliated Hospital of Changchun University of Traditional Chinese Medicine, 130021 Changchun, Jilin, China.
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