The structural and functional aspects of exercise-induced cardiac remodeling and the impact of exercise on cardiovascular outcomes.

William K Cornwell, Natalie A Van Ochten, Emmett Suckow, Lindsay Forbes

Journal: Annals of medicine 2025;57(1):2499959

PMID: 40377449

Abstract

The relationship between exercise training and overall cardiovascular health is well defined, with associated reductions in incidence of cardiovascular disease and comorbidities such as hypertension, diabetes mellitus, cholesterol profile, body weight, and even some forms of cancer. In this regard, an exercise prescription is an effective tool to decrease all-cause mortality and improve overall health. As providers, properly educating patients on the type, amount, and intensity of exercise is important to ensure patients meet recommended exercise metrics to experience these health benefits. This review provides a concise, but comprehensive overview of the structural and functional aspects of exercise-induced cardiac remodeling, current recommended guidelines for exercise with supporting data, as well as the impact exercise has on various cardiovascular outcomes.

Address: Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.; Department of Medicine-Cardiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.; Clinical Translational Research Center, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.; Department of Medicine-Pulmonary and Critical Care Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Bant logo

© Copyright 2026, Nutrition Evidence

NED wishes to thank the following organisations for their support:

We use cookies to improve your experience and analyze site traffic with Google Analytics. By continuing to use our site, you agree to our use of cookies. Learn more.