Sergio Miras-Moreno, Pablo Jiménez-Martínez, Carlos Alix-Fages, Danica Janicijevic, Sara Chacón-Ventura, Juan J Martín-Olmedo, Amador García-Ramos, Magdalena Cwiklinska, María Dolores Morenas-Aguilar
Journal: Clinical nutrition ESPEN 2025;65():305-314
PMID: 39644922
BACKGROUND & AIMS
The aim of this study was to investigate the potential ergogenic effects of intra-session supplementation of highly branched cyclic dextrin (HBCD) on mechanical (number of repetitions completed and repetition velocity), metabolic (lactate concentration), and perceptual (gastrointestinal complaints and ratings of perceived exertion [RPE]) responses to resistance training.
METHODS
This study used a randomized, double-blinded, placebo-controlled crossover study design. Thirty physically active individuals (15 men and 15 women) completed two experimental sessions that only differed in the supplement condition (placebo or HBCD). In each experimental session, subjects were prescribed five sets of eight repetitions with the 12-repetition maximum load during the bench press, bench pull, and squat exercises. During the sessions, participants consumed a total of 750 mL of the beverage, which either contained diluted 45 g of cyclic dextrin (HBCD condition) or only 2.5 g of the calorie-free excipients (placebo condition). The supplement (placebo or HBCD) was ingested during the inter-set rest periods (50 mL before each set).
RESULTS
The main findings indicated that intra-session HBCD supplementation (i) was well-tolerated without causing gastrointestinal complaints, (ii) led to improved repetition velocity during RT in men but not in women, (iii) tended to generate comparable or higher lactate values, and (iv) did not significantly influence the perception of fatigue.
CONCLUSIONS
These results suggest that HBCD can be considered an ergogenic supplement, particularly for enhancing mechanical performance in men, without noticeably affecting the perception of fatigue or discomfort.
Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Full Text Sources:
Medical:
Full Text Sources:
© Copyright 2026, Nutrition Evidence
We use cookies to improve your experience and analyze site traffic with Google Analytics. By continuing to use our site, you agree to our use of cookies. Learn more.