Rare dysfunctional SCN2A variants are associated with malformation of cortical development.

Address: Division of Neurology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; The Epilepsy Neurogenetics Initiative, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.; Department of Radiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; The University of California, Berkeley, California, USA.; Child Neurology, Epilepsy and Movement Disorders, Bambino Gesù, IRCCS Children's Hospital, Rome, Italy.; Department of Neuroscience and Medical Genetics, Meyer Children's Hospital IRCCS, Florence, Italy.; University of Florence, Florence, Italy.; Department of Pediatrics, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota, USA.; Neonatology and Neonatal Intensive Care Unit, Children's Hospital, ASST-Spedali Civili of Brescia, Brescia, Italy.; Unit of Child Neurology and Psychiatry, ASST-Spedali Civili of Brescia, Brescia, Italy.; Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, UK.; Department of Neurology, The University of California, Sacramento, California, USA.; Division of Neurology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; The Epilepsy Neurogenetics Initiative, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Neurology, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.; Department of Biomedical and Health Informatics (DBHi), Children's Hospital of Philadelphia, Pennsylvania, USA.; Division of Neurology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Neuroscience, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.; Division of Neurology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; The Epilepsy Neurogenetics Initiative, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Biomedical and Health Informatics (DBHi), Children's Hospital of Philadelphia, Pennsylvania, USA.; Department of Neuroscience, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.