The effect of hypohydration before and different rehydration strategies after severe intensity exercise on post-exercise hypotension in men.

Tomomi Fujimoto, Xia Wei, Narihiko Kondo, Jingliang Chen, Jason Kai Wei Lee, Tze-Huan Lei, Faming Wang, Beverly Tan, Toby Mündel, Naoto Fujii, Tatsuro Amano, Richie Goulding, James Cotter

Journal: European journal of applied physiology 2025;125(7):1971-1982

PMID: 40035827

Abstract

We examined the effect of 12 h of fluid deprivation before, and three different rehydration strategies (none, fixed volume, and ad libitum drinking) after exercise on post-exercise hypotension (PEH) in 12 normotensive Asian men. The participants underwent four experimental trials, comprising euhydration (Eu), dehydration only (De), dehydration with fixed fluid intake (De + Fixed) and dehydration with ad libitum fluid intake (De + Ad). The participants completed one of the dehydration trials at the severe intensity domain until volitional exhaustion. All other trials were strictly matched for the time to exhaustion reported in the dehydration trial (698 ± 179 s), with a 1-h recovery in all trials. The dehydration trials (De, De + Fixed and De + Ad) induced higher resting plasma osmolality (291 ± 4, 294 ± 6, 294 ± 4 vs. 287 ± 4 mOsm/kg, respectively), urine specific gravity and haematocrit (all P < 0.03) than Eu. The peak reduction in post-exercise diastolic blood pressure was larger in De (- 12 ± 2 mm Hg) than in Eu (- 6 ± 1 mm Hg), De + Fixed (- 4 ± 2 mm Hg) and De + Ad (- 5 ± 2 mm Hg), as was the reduction in mean arterial pressure (De: - 11 ± 2 vs - 7 ± 1, - 5 ± 1 and - 5 ± 1 mm Hg, all P < 0.05). These reductions did not differ across Eu, De + Fixed and De + Ad (all P > 0.80). No effects of dehydration on systolic pressure were observed (P = 0.06). Dehydration exacerbated PEH whilst fixed and ad libitum drinking during the post-exercise period were equally effective at mitigating hypotension in Asian men.

© 2025. The Author(s).

Address: Centre for Molecular Biosciences and Non-Communicable Diseases, Xi'an University of Science and Technology, Xi'an, China.; College of Physical Education, Hubei Normal University, Huangshi, China.; Department of Human Movement Sciences, Faculty of Behavioral and Human Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Amsterdam, the Netherlands.; School of Physical Education, Sport and Exercise Sciences, University of Otago, Dunedin, New Zealand.; Heat Resilience and Performance Centre, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Heat Resilience and Performance Centre, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Faculty of Education, Niigata University, Niigata, Japan.; Department of Health and Sports, Niigata University of Health and Welfare, Niigata, Japan.; Institute of Sport and Sciences, University of Tsukuba, Tsukuba, Japan.; Laboratory for Applied Human Physiology, Graduate School of Human Development and Environment, Kobe University, Kobe, Japan.; Hydration Exercise and Temperature Laboratory, Department of Kinesiology, Brock University, St. Catharines, Canada. [email protected].
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