The Co-Occurrence of Autism and Avoidant/Restrictive Food Intake Disorder (ARFID): A Prevalence-Based Meta-Analysis.

Jess Kerr-Gaffney, Helen Sharpe, Fiona Duffy, Michelle Sader, Annabel Weston, Kyle Buchan, Karri Gillespie-Smith

Journal: The International journal of eating disorders 2025;58(3):473-488

PMID: 39760303

Abstract

OBJECTIVE

Avoidant/restrictive food intake disorder (ARFID) is a feeding and eating disorder characterized by extensive avoidance and/or restriction of food. Existing research demonstrates that ARFID is over-represented in Autistic populations and vice-versa, with both groups exhibiting shared characteristics. This meta-analysis investigated the co-occurrence between ARFID and autism via determination of autism prevalence in ARFID populations, and ARFID prevalence in Autistic groups.

METHOD

This review systematically identified literature evaluating those with ARFID and Autistic individuals. Literature was searched for using SCOPUS, MEDLINE, and Web of Science. Selected publications included Autistic individuals and those with ARFID who either received a formal diagnosis of autism and/or ARFID or met clinical threshold cut-off scores on validated autism and/or ARFID questionnaires. Prevalence was reported in proportion-based values alongside 95% confidence intervals (CIs).

RESULTS

This meta-analysis identified 21 studies (kARFID = 18 papers; kAutism = 3 papers) comprising of n = 7442 participants (nARFID = 1708; nAutism = 5734). Prevalence of autism diagnoses was 16.27% in those with ARFID (95% CI = 8.64%-28.53%), and ARFID prevalence in Autistic groups was 11.41% (95% CI = 2.89%-35.76%). Gender and ethnicity served as significant sources of heterogeneity in ARFID papers. There was insufficient data to provide comparator values or prevalence across study population and distinct underpinning drivers of ARFID.

DISCUSSION

Meta-analytic findings highlight significant rates of co-occurrence between autism and ARFID, suggesting that in clinical settings, it may be beneficial to consider screening Autistic individuals for ARFID and vice-versa. Future research should further investigate co-occurrence across ARFID profiles, gender, and ethnicity.

© 2025 The Author(s). International Journal of Eating Disorders published by Wiley Periodicals LLC.

Address: School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, UK.; The Eating Disorders and Autism Collaborative (EDAC), University of Edinburgh, Edinburgh, UK.; School of Health in Social Science, University of Edinburgh, Edinburgh, UK.; The Eating Disorders and Autism Collaborative (EDAC), University of Edinburgh, Edinburgh, UK.; School of Health in Social Science, University of Edinburgh, Edinburgh, UK.; The Eating Disorders and Autism Collaborative (EDAC), University of Edinburgh, Edinburgh, UK.; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; The Eating Disorders and Autism Collaborative (EDAC), University of Edinburgh, Edinburgh, UK.; School of Health in Social Science, University of Edinburgh, Edinburgh, UK.; NHS Lothian Child and Adolescent Mental Health Services, Edinburgh, UK.
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