Protein post-translational modifications (PTM) unlocking resilience to abiotic stress in horticultural crops: A review.

Horticultural crops are extensively cultivated throughout the world as crucial economical crops, encompassing fruits, vegetables, ornamentals, medicinal and beverage plants, for purposes such as food supply, special nutrition provision, medical application or aesthetic enjoyment. However, abiotic stress triggered by extreme climate change, such as excessive salt and prolonged drought, directly leads to the decline of nutritional quality of horticultural crops, contributing to the shortage of high-quality fruits. Post-translational modifications of proteins, such as phosphorylation and ubiquitination, can alter protein characteristics by adding specific groups to amino acids, which in turn impacts protein stability to regulate plant growth and development as well as environmental stress. Consequently, the revelation of the molecular mechanism of horticultural crops response to abiotic stress at post-translational modification level (PTMs) has always attracted a lot of scholars, as it is crucial for the development and breeding of climate-resilient apple varieties. At PTMs level, this review focuses on summarizing research advancements in horticultural crops responses to environmental stress, including drought, salt, cold, high temperature and iron (Fe) deficiency, with emphasis on sucrose non-fermentative 1 (SNF1) associated protein kinases (SnRKs) and mitogen-activated protein kinase (MAPK) cascade mediated phosphorylation, E3 ubiquitin ligases and BTB/TAZ subfamily BT2 mediated ubiquitination, SIZ1 SUMO E3 ligase mediated sumoylation, Nitric oxide (NO) mediated S-nitrosylation, and other forms of PTMs including protein glycosylation and lysine acetylation. In conclusion, this review adopts protein modification as an entry point to illuminate the mechanism of key genes regulating abiotic stress at PTMs level, providing a foundation for the cultivation of horticultural crops with superior resistance.

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