Advances in Coronary CT Angiography: Applications and Implications for Coronary Artery Disease.

Coronary artery disease (CAD) remains a leading cause of morbidity and mortality worldwide, necessitating advancements in diagnostic techniques. Coronary CT angiography (CCTA) has emerged as a pivotal non-invasive tool for evaluating coronary artery anatomy and detecting atherosclerotic plaque burden with high spatial resolution. This review explores the evolution of CCTA, highlighting its technological advancements, clinical applications, and challenges. Key innovations such as multidetector CT, photon-counting CT, and functional assessment tools like FFR-CT have enhanced CCTA's diagnostic and prognostic capabilities. Despite these advancements, issues related to radiation exposure, iodinated contrast, and patient-specific limitations persist. Future directions include the development of novel imaging biomarkers and strategies to minimize radiation exposure. By synthesizing existing literature and recent developments, this paper provides a comprehensive understanding of CCTA's role in contemporary CAD management.