Biotechnological Production of Carotenoids Using .

Xiao-Jun Ji, Lu Lin, Wenjuan Li, Mei-Li Sun, Kaifeng Wang, Jie Mai, Aiqi Liu

Journal: Journal of agricultural and food chemistry 2025;73(12):7034-7045

PMID: 40079666

Abstract

Carotenoids are a group of tetraterpenoid natural products with a variety of physiological activities, which led to their application in food, cosmetics, agriculture, and other industries with broad market prospects. The fermentation of carotenoids using engineered microbial hosts has emerged as an efficient, sustainable, and environmentally friendly production method with significant potential for further development. (), an unconventional oleaginous yeast, has intrinsic advantages as a host strain for the production of carotenoids. This review outlines the functions of some well-studied carotenoids, including lycopene, β-carotene, and astaxanthin. Furthermore, the biotechnological strategies for carotenoid production in are categorized and summarized. Finally, potentially feasible future strategies for further improvement of carotenoid production in are also prospected.

Address: State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, No. 30 South Puzhu Road, Nanjing 211816, People's Republic of China.

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