Phytochemical and Pharmacological Insights into Boriss.: A Promising Antimicrobial Plant.

Gulnaz Seitimova, Aknur Turgumbayeva, Alma Amangeldi, Zhanar Nurgaliyeva, Baiken Baimakhanova, Amankeldi Sadanov, Gul Baimakhanova, Diana Tluebekova, Zere Turlybaeva, Irina Ratnikova, Roza Seisebayeva, Botagoz Ussipbek, Lyazzat Umbetyarova, Akerke Amirkhanova

Journal: Molecules (Basel, Switzerland) 2025;30(3):

PMID: 39942616

Abstract

Boriss., a species native to Central Asia, has garnered significant attention for its diverse phytochemical profile and antimicrobial potential. This review synthesizes current knowledge on the antimicrobial activities of , focusing on its essential oils and other bioactive constituents. The study contextualizes the importance of natural antimicrobials in the era of rising antibiotic resistance and highlights the plant's traditional use in ethnomedicine. The main methodologies explored include gas chromatography-mass spectrometry (GC-MS) for phytochemical characterization and various in vitro assays to assess antimicrobial efficacy against bacterial and fungal pathogens. The essential oils of demonstrate a broad spectrum of activity, attributed to compounds such as menthol, menthone, and carvone. Other phytochemicals, including sesquiterpenes and terpenoids, also contribute to its bioactivity. The review underscores the potential of as a source of novel antimicrobial agents and calls for further research into its mechanisms of action, bioavailability, and safety profiles. The findings position as a promising candidate for developing plant-based antimicrobial formulations, addressing critical needs in healthcare and food preservation.

Address: Research and Production Center for Microbiology and Virology LLP, Bogenbay Batyr St. 105, Almaty 050010, Kazakhstan.; School of Pediatrics, Department of Outpatient Pediatrics. S.D. Asfendiyarov Kazakh National Medical University, Almaty 050010, Kazakhstan.; Department of Biophysics, Biomedicine and Neuroscience, Al-Farabi Kazakh National University, Almaty 050040, Kazakhstan.; School of Pharmacy, S.D. Asfendiyarov Kazakh National Medical University, Tole-bi 94, Almaty 050012, Kazakhstan.; Faculty of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, Almaty 050040, Kazakhstan.; Higher School of Medicine, Al-Farabi Kazakh National University, Almaty 050040, Kazakhstan.
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