A Comprehensive Review of Adenoviral Conjunctivitis: Exploring the Role of Povidone-iodine in Treatment.

Riya Patel, Hamza Khan, Sadiq Shaikh, Hassaam S Choudhry, David Mothy, Mohammad H Dastjerdi

Journal: International ophthalmology clinics 2025;65(2):1-11

PMID: 40116403

Abstract

This review highlights recent developments in the management of adenoviral conjunctivitis (AC), the most common cause of viral conjunctivitis, which can lead to serious complications like subepithelial infiltrates, pseudomembrane formation, and conjunctival scarring. This paper discusses the pathogenic serotypes, particularly those responsible for epidemic keratoconjunctivitis (EKC), and new treatment options, with a focus on povidone-iodine (PVP-I). Diagnosis of AC is primarily based on clinical evaluation, although laboratory testing and imaging may support the assessment. Recent investigation suggests that PVP-I is a promising treatment option, as it can reduce viral load and alleviate symptoms, with minimal adverse effects. However, further research is needed to refine the optimal treatment protocols for PVP-I.

Address: Department of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, Newark, NJ.

DOI: 10.1097/IIO.0000000000000556

Link outs

Subscription / membership required

Full Text Sources:

MeSH Terms: Humans, Povidone-Iodine, Conjunctivitis, Viral, Anti-Infective Agents, Local, Adenovirus Infections, Human, Eye Infections, Viral