Standardization of gut microbiome analysis in sports.

Laura Mancin, Ian Rollo, Joao Felipe Mota, Antonio Paoli, Javier T Gonzalez, Adam J Collins, Sara Berry, Maria Antonia Lizarraga, Segata Nicola

Journal: Cell reports. Medicine 2024;5(10):101759

PMID: 39368478

Abstract

The gut microbiome plays a significant role in physiological functions such as nutrient processing, vitamin production, inflammatory response, and immune modulation, which, in turn, are important contributors to athlete health and performance. To date, the interpretation, discussion, and visualization of microbiome results of athletes are challenging, due to a lack of standard parameters and reference data for collection and comparison. The purpose of this perspective piece is to provide researchers with an easy-to-understand framework for the collection, analysis, and data management related to the gut microbiome with a specific focus on athletic populations. In the absence of a consensus on microbiome research in the sports field, we hope that these considerations serve as foundational "best practice." Adherence to these standard operating procedures will accelerate the path toward improving the quality of data and ultimately our understanding of the influence of the gut microbiome in sport settings.

Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.

Address: Department of Biomedical Sciences, University of Padua, Padua, Italy; Human Inspired Technology Research Center HIT, University of Padua, Padua, Italy. Electronic address: [email protected].; Department of Biomedical Sciences, University of Padua, Padua, Italy; Human Inspired Technology Research Center HIT, University of Padua, Padua, Italy.; Department of Nutritional Sciences, King's College London, London, UK.; Department for Health, University of Bath, BA2 7AY Bath, UK.; Medical, Sport Science and Health Department, FC Barcelona, Barcelona, Spain.; APC Microbiome Ireland, Department of Medicine, School of Microbiology, University College Cork, T12 YT20 Cork, Ireland.; Centre for Integrative Biology, University of Trento, Trento, Italy.; Gatorade Sports Science Institute, PepsiCo Life Sciences, Global R&D, Leicestershire, UK; School of Sports Exercise and Health Sciences, Loughborough University, Leicestershire, UK.
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