Malignant perivascular epithelioid cell tumor involving the prostate.

Chin-Chen Pan, An-Hang Yang, Hung Chiang

Journal: Archives of pathology & laboratory medicine 2003;127(2):E96-8

PMID: 12562263

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Abstract

Perivascular epithelioid cell tumor (PEComa) is a neoplasm chiefly composed of HMB-45-positive epithelioid cells with clear-to-granular cytoplasm and a perivascular distribution. We describe such a tumor involving the prostate and seminal vesicle in a 46-year-old man. The tumor had characteristic histologic features of PEComa. Immunohistochemically, the tumor cells were positive for HMB-45 but negative for epithelial markers, Melan-A, and S100 protein. The tumor behaved in a malignant fashion, and the patient died of the disease 4 years after diagnosis.

Address: Department of Pathology, National Yang-Ming University, and Veterans General Hospital-Taipei, Taipei, Taiwan. [email protected]

DOI: 10.5858/2003-127-e96-MPECTI

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https://medlineplus.gov/prostatecancer.html

MeSH Terms: Antigens, Neoplasm, Biomarkers, Tumor, Epithelioid Cells, Humans, Immunohistochemistry, MART-1 Antigen, Male, Melanoma-Specific Antigens, Middle Aged, Neoplasm Proteins, Prostatic Neoplasms, S100 Proteins, Seminal Vesicles, Smooth Muscle Tumor, Vascular Neoplasms