Phytochemical and pharmacological properties of the genus from 2016 to 2023.

Ah-Reum Han, Isoo Youn, Donglan Piao, Hwaryeong Lee, Hyunkyung Kwak, Yeju Lee, Joo-Won Nam, Eun Kyoung Seo

Journal: Natural product reports 2024;41(9):1346-1367

PMID: 38717742

Abstract

Covering 2016 up to the end of 2023 is the largest genus of flowering plants in the ginger family, Zingiberaceae, and comprises about 500 species. Many are commonly cultivated ornamental plants, and some are used as spices or traditional medicine to treat inflammation, hyperlipidemia, and cancers. However, only a few comprehensive reviews have been published on the phytochemistry and pharmacology of this genus, and the latest review was published in 2017. In this review, we provide an extensive coverage of the studies on species reported from 2016 through 2023, including newly isolated compounds and potential biological effects. The present review article shows that species have a wide spectrum of pharmacological activities, most due to the activities of diarylheptanoids, terpenoids, flavonoids, and phenolics.

Address: Graduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul 03760, Republic of Korea. [email protected].; Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute (KAERI), Jeongeup-si, Jeollabuk-do 56212, Republic of Korea.; College of Pharmacy, Yeungnam University, Gyeongsan-si, Gyeongsangbuk-do 38541, Republic of Korea.

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