Shaping the Future of Functional Foods: Using 3D Printing for the Encapsulation and Development of New Probiotic Foods.

Josemar Gonçalves de Oliveira Filho, Mariana Buranelo Egea, Mateus Kawata Salgaço, Larissa Graziele Rauber Duarte, Diego Oliveira Bonfim, Luiz Henrique Caparelli Mattoso

Journal: Probiotics and antimicrobial proteins 2025;17(3):1295-1307

PMID: 39419915

Abstract

Consumers have been demanding foods that, besides providing nutrition, bring some health benefits, known as functional foods. The insertion of probiotics in foods is a strategy for developing functional foods. Still, it has been a challenge because these matrices have different pHs and undergo different process temperatures and times that can reduce the viability of these microorganisms. In this sense, encapsulation using 3D printing emerges to protect probiotic microorganisms and ensure that they reach the intestine viable and carry out the expected beneficial action. Thus, this review evaluates the current advancements in 3D printing to encapsulate and develop novel probiotic foods. Research has shown that 3D printing effectively encapsulates probiotic microorganisms, preserving their viability throughout the gastrointestinal tract. Studies have proven the effectiveness of 3D printing encapsulation in protecting probiotics during processing, storage, and digestion. Innovative formulations for 3D bioprinted products with probiotics, such as food structures based on cereals, mashed potatoes, and cream, have been developed. Producing products with shelf life and combining applications of phytochemicals and probiotics aims to improve personalized nutrition, textural characteristics, and sensory attributes of the foods produced by this emerging approach. Therefore, 3D printing of foods with probiotics has the potential to create new products that meet this demand.

© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Address: Brazilian Agricultural Research Corporation, Embrapa Instrumentation, São Carlos, SP, Brazil.; School of Food Engineering, State University of Campinas (UNICAMP), Campinas, 13083-862, Brazil.; Department of Electrical and Computer Engineering, São Carlos School of Engineering, University of São Paulo, São Carlos, Brazil.; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, 14800-903, Brazil.; Goiano Federal Institute of Education, Science and Technology, Campus Rio Verde, Rio Verde, Goiás, Brazil. [email protected].

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