Early wound healing in guided bone regeneration procedures using sodium hyaluronate and a pool of amino acids: a randomized clinical trial.

BACKGROUND

Soft tissue healing is of paramount importance when guided bone regeneration techniques are used, as early exposure of the membrane could affect the results.

METHODS

In this randomized clinical trial, enrolling 20 patients, a gel rich in hyaluronic acid and amino acids was used to promote wound healing after a ridge augmentation procedure. The Early Wound Healing Index - EHS was used to assess soft tissue healing by primary intention following surgery at 1, 3, 7 and 14 days.

RESULTS

Results showed faster tissue healing when hyaluronic acid mixed with amino acids was used, and also a lower perception of pain by patients measured with a VAS scale.

CONCLUSIONS

These data suggest the creation of larger research studies that can support the use of biologics for early soft tissue healing.