Are chlorella viruses a rich source of ion channel genes?

Ming Kang, Anna Moroni, Sabrina Gazzarrini, James L Van Etten

Journal: FEBS letters 2003;552(1):2-6

PMID: 12972143

Abstract

Plaque-forming dsDNA (>330 kb) viruses that infect certain unicellular, eukaryotic chlorella-like green algae contain approximately 375 protein-encoding genes. These proteins include a 94 amino acid K+ channel protein, called Kcv, as well as two putative ligand-gated ion channels. The viruses also encode other proteins that could be involved in the assembly and/or function of ion channels, including protein kinases and a phosphatase, polyamine biosynthetic enzymes and histamine decarboxylase.

Address: Department of Plant Pathology, University of Nebraska, Lincoln, NE 68583-0722, USA.

DOI: 10.1016/s0014-5793(03)00775-0

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MeSH Terms: Amino Acid Sequence, Carboxy-Lyases, Chlorella, DNA Ligases, Genome, Viral, Histamine, Ion Channel Gating, Ion Channels, Ligands, Models, Genetic, Molecular Sequence Data, Phycodnaviridae, Polyamines, Potassium, Potassium Channels, Protein Kinases, Sequence Homology, Amino Acid, Transcription, Genetic, Viral Proteins