Atul Dhingra, Sanjay Kalra, Nitin Kapoor
Journal: JPMA. The Journal of the Pakistan Medical Association 2025;75(4):654-656
PMID: 40269380
Glucosarcopenia, or sarcopenia coexisting with diabetes, is a common condition. Caused by various factors, including poor glucose control, as well as some glucoselowering therapies, sarcopenia negatively impacts quality of life and long-term health. Nandrolone, or 19- nortestosterone, is a selective anabolic receptor modulator (SARM), classified as an anabolic-androgenic steroid (AAS). A review of its pharmacological properties suggests that it may be used as therapy for sarcopenia, along with medical nutrition therapy and resistance exercise training. This review suggests a practical and pragmatic approach towards ensuring safe and smart usage of nandrolone in glucosarcopenia management.
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