GLI1-altered mesenchymal tumor of tongue: a case report and literature review.

Wenting Wu, Na Xie, Yousheng Huang, Yang Weng

Journal: Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 2024;42(6):822-827

PMID: 39610081

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Abstract

GLI1-altered mesenchymal tumors are a relatively rare type of mesenchymal tumor that is common in the head and neck. It is a newly added tumor type in the World Health Organization Tumor Classification of Head and Neck (5th edition). This article reports a case ofGLI1alteredmesenchymal tumor occurring at the left tongue and reviews the relevant literature to summarize the pathological morphological characteristics, immunophenotype, molecular changes, clinical manifestations, and prognosis of the disease.

Address: Dept. of Stomatology, Hainan Medical University, Haikou 571199, China.; Dept. of Pathology, The First Affiliated Hospital of Hainan Medical University, Haikou 570102, China.; Dept. of Pathology, The First Affiliated Hospital of Hainan Medical University, Haikou 570102, China.; Shenzhen Longhua District Central Hospital, Shenzhen 518110, China.; Dept. of Pathology, The First Affiliated Hospital of Hainan Medical University, Haikou 570102, China.

DOI: 10.7518/hxkq.2024.2024098

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MeSH Terms: Humans, Tongue Neoplasms, Zinc Finger Protein GLI1, Mesenchymoma