Recent developments in delirium after oral and maxillofacial free-flap reconstruction.

Wuxia Zhang, Yanming Ren, Rui Zhang, Li Li, Jingya Yu, Yuekang Zhang

Journal: Journal of stomatology, oral and maxillofacial surgery 2025;126(1):102045

PMID: 39244025

Full Text on Elsevier Science View on PubMed

Abstract

Postoperative delirium (POD), a common complication following surgery and anesthesia, is particularly prone to occur after reconstruction surgery in the oral and maxillofacial region. The occurrence of POD seriously affects the incidence of postoperative complications, the survival of free flaps, the length of hospital stays, and brings great pain to patients and their families, and even increases perioperative mortality. Currently, a large number of studies have reported on the risk factors for POD after oral and maxillofacial free-flap reconstruction. Multiple independent risk factors have been identified, including age, history of excessive alcohol consumption, and perioperative nutritional status. This review summarizes the relevant literature and hopes to provide insights for the prevention of POD in high-risk patients.

Address: Department of Neurosurgery, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.; Clinic Trial Center, West China Hospital, Sichuan University, Chengdu, China.; West China School of Nursing, Sichuan University, Chengdu, China.; Department of Outpatient, West China Hospital, Sichuan University, Chengdu, China. Electronic address: [email protected].; Department of Neurosurgery, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China. Electronic address: [email protected].

DOI: 10.1016/j.jormas.2024.102045

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MeSH Terms: Male, Female, Middle Aged, Aged, Aged, 80 and over, Mouth Neoplasms, Risk Factors, Free Tissue Flaps, Orthognathic Surgical Procedures, Postoperative Cognitive Complications, Delirium, Incidence, Nutritional Status, Age Factors, Alcohol Drinking, Perioperative Period, Length of Stay, Humans