Advances in Exercise and Dietary Interventions for Peripheral Arterial Disease.

Pei-Pei Han, Kai Zheng

Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 2025;46(6):932-939

PMID: 39773512

Abstract

Peripheral arterial disease(PAD)is a common atherosclerotic cardiovascular disease.The patients with this disease experience pain during exercise,which is relieved after rest.Exercise interventions,dietary interventions,and combined interventions can treat PAD via different mechanisms.Aerobic exercise,resistance exercise,and combined exercise can increase muscle strength and improve cardiorespiratory fitness to regulate vascular endothelial adhesion.Dietary interventions,such as dietary fibre,polyunsaturated fatty acids,and antioxidants,can affect plaque formation via anti-inflammatory and antioxidant mechanisms.The combined exercise and dietary interventions can have synergistic effects.This article reviews the relationship between the two interventions and PAD and describes the current status of research on different interventions,providing a scientific basis for the prevention and treatment of PAD.

Address: College of Rehabilitation Medicine,Shanghai University of Medicine and Health Sciences,Shanghai 200000,China.; School of Health Science and Engineering,University of Shanghai for Science and Technology,Shanghai 200000,China.; College of Rehabilitation Medicine,Shanghai University of Medicine and Health Sciences,Shanghai 200000,China.
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