Casey Schoenlank, Alphonsa Thomas, Raisa Bakshiyev, SuAnn Chen
Journal: Physical medicine and rehabilitation clinics of North America 2025;36(2):361-370
PMID: 40210367
Osteoporosis is the most common metabolic bone disease across the world resulting from compromised bone microstructure and decreased bone mineral density. It primarily impacts postmenopausal women over 50 years placing them at heightened risk for fractures. The pathophysiology involves an imbalance in bone resorption and production. Nonpharmacologic approaches can bolster a treatment plan, namely with alterations in nutrition and exercise. The first clinical indication of osteoporosis is typically a fracture, which is mostly found to be a vertebral compression fracture. Osteoporosis is a highly treatable and preventable condition that can result in high morbidity and mortality if not adequately addressed.
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