Effectiveness of DASH Diet versus Other Diet Modalities in Patients with Metabolic Syndrome: A Systematic Review and Meta-Analysis.

Hector Gutierrez-Espinoza, Pablo Nova-Baeza, Gustavo Oyanedel-Amaro, Mathias Orellana-Donoso, Juan José Valenzuela-Fuenzalida, Vicente Silva Bravo, Laura Moyano Valarezo, María Fernanda Delgado Retamal, Josefa Matta Leiva, Alejandro Bruna-Mejías, Alejandra Suazo-Santibañez

Journal: Nutrients 2024;16(18):

PMID: 39339654

Abstract

BACKGROUND

Metabolic syndrome refers to the coexistence of several known cardiovascular risk factors, including insulin resistance, obesity, atherogenic dyslipidemia, and hypertension. These conditions are interrelated and share underlying mediators, mechanisms, and pathways. Improvement in dietary habits has been shown to improve metabolic parameters in patients undergoing treatment with different diets.

METHODS

A systematic search in different databases was realized using the keywords "Metabolic syndrome", "X syndrome", "Dash dietary" and "Dash diet". Finally, six studies were included in this meta-analysis.

RESULTS

All articles comparing the DASH diet vs. other diet modalities reported significant differences in favor of the DASH diet on Systolic blood pressure (SBP) (standardized mean difference [SMD] = -8.06, confidence interval [CI] = -9.89 to -7.32, and < 0.00001), Diastolic blood pressure (SMD = -6.38, CI = -7.62 to -5.14, and < 0.00001), Cholesterol HDL (SMD = 0.70, CI = 0.53 to 0.88, and < 0.00001) and Cholesterol LDL (SMD = -1.29, CI = -1.73 to -0.85, and < 0.00001) scales.

CONCLUSIONS

The DASH diet has been shown to be beneficial in altered parameters in patients with MS, and the resulting improvements can significantly affect the daily health of these patients. We therefore recommend that professionals who manage these pathologies promote the use of the DASH diet for the management of specific symptoms.

Address: Departamento de Morfología, Facultad de Medicina, Universidad Andrés Bello, Santiago 7591538, Chile.; Departamento de Ciencias Química y Biológicas, Facultad de Ciencias de la Salud, Universidad Bernardo O'Higgins, Santiago 8370993, Chile.; Departamento de Morfología, Facultad de Medicina, Universidad Andrés Bello, Santiago 7591538, Chile.; Departamento de Morfología, Facultad de Medicina, Universidad Andrés Bello, Santiago 7591538, Chile.; Escuela de Medicina, Universidad Finis Terrae, Santiago 7501015, Chile.; Department of Morphology and Function, Faculty of Health and Social Sciences, Universidad de Las Americas, Santiago 8370040, Chile.; Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Santiago 8910060, Chile.; One Health Research Group, Universidad de Las Americas, Quito 170124, Ecuador.
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