Extraction and Synthesis of Typical Carotenoids: Lycopene, β-Carotene, and Astaxanthin.

Jingyi Ye, Wenge Yang, Wenhui Li, Jie Cui, Jinchi Jiang, Jian Zhang, Yuxuan Jiang, Yadong Hu, Xinghu Zhou, Mingzhou Yu, Yiyang Yu, Jingwei Yang, Yonghong Hu

Journal: Molecules (Basel, Switzerland) 2024;29(19):

PMID: 39407479

Abstract

Carotenoids are tetraterpene compounds acting as precursors to vitamin A, with functions that include protecting eyesight, enhancing immunity, promoting cell growth and differentiation, and providing antioxidative benefits. Lycopene, β-carotene, and astaxanthin are particularly critical for health and have diverse applications in food, health products, and medicine. However, natural carotenoids are encased within cell structures, necessitating mechanical methods to disrupt the cell wall for their extraction and purification-a process often influenced by environmental conditions. Thus, improving the efficiency of carotenoid extraction from natural resources is of great interest. This review delves into the research progress made on the extraction processes, structures, and biological functions of carotenoids, focusing on lycopene, β-carotene, and astaxanthin. Traditional extraction methods primarily involve organic solvent-assisted mechanical crushing. With deeper research and technological advancements, more environmentally friendly solvents, advanced machinery, and suitable methods are being employed to enhance the extraction and purification of carotenoids. These improvements have significantly increased extraction efficiency, reduced preparation time, and lowered production costs, laying the groundwork for new carotenoid product developments.

Address: College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, China.; College of Food Science and Light Industry, Nanjing Tech University, Nanjing 211816, China.; Jiangsu Innovation Center of Marine Bioresource, Jiangsu Coast Development Investment Co., Ltd., Nanjing 210019, China.; Key Laboratory of Coastal Salt Marsh Ecosystems and Resources, Ministry of Natural Resources, Nanjing 210006, China.; School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing 211816, China.; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, China.; College of Food Science and Light Industry, Nanjing Tech University, Nanjing 211816, China.
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