Optimizing Care: Integrative Oncology in Myeloproliferative Neoplasm.

Shagun Singh, Supriya Peshin, Ashley Larsen, Krisstina Gowin

Journal: Current oncology reports 2024;26(10):1135-1145

PMID: 38967863

Abstract

PURPOSE OF REVIEW

Myeloproliferative neoplasm (MPN) burdens the lives of those affected. MPN patients endure significant impacts on their physical, psychological, and social well-being. While pharmacological interventions offer some disease and symptom control, they often have unfavorable side effects. This review explores the potential of Integrative Oncology (IO) therapies in managing MPNs and their associated symptoms.

RECENT FINDINGS

IO is dedicated to augmenting conventional treatments through integrating interventions targeting the mind, body, nutrition, supplements, and other supportive care therapies. Several small studies suggest the benefit of an IO approach in MPN patients. These benefits are postulated to be modulated through enhanced physical capacity, reduced disease-related inflammation, subconscious mind training, and gut microbiome modulation. By combining IO with evidence-based pharmacological treatments, the potential exists to enhance the quality of life and clinical outcomes for individuals with MPNs. Future research should prioritize well-powered studies, including diverse demographics and symptom profiles, with appropriate study duration, to draw definite conclusions regarding the observed effects.

© 2024. The Author(s).

Address: Internal Medicine, Banner University Medical Center, Tucson, AZ, USA.; Norton Community Hospital, Ballad Health, Norton, VA, USA.; Department of Medicine, University of Arizona, Tucson, AZ, USA.; Department of Medicine, Hematology Oncology, University of Arizona, 1501 N Campbell Ave, Tucson, AZ, 85724, USA. [email protected].

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