Italian guidelines for the diagnosis and management of colonic diverticulosis and diverticular disease.

Maria Teresa Viggiani, Costantino Sgamato, Bastianello Germanà, Marilia Carabotti, Bruno Annibale, Carola Severi, Rosario Cuomo, Gioacchino Leandro, Sergio Peralta, Antonio Amato, Benedetta Beltrame, Gian Andrea Binda, Luigi Pasquale

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2024;56(12):1989-2003

PMID: 39004551

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Abstract

Colonic diverticulosis and diverticular disease are among the most common gastrointestinal disorders encountered in clinical practice. These Italian guidelines focus on the diagnosis and management of diverticulosis and diverticular disease in the adult population, providing practical and evidence-based recommendations for clinicians. Experts from five Italian scientific societies, constituting a multidisciplinary panel, conducted a comprehensive review of meta-analyses, systematic reviews, randomised controlled trials, and observational studies to formulate 14 PICO questions. The assessment of the quality of the evidence and the formulation of the recommendations were carried out using an adaptation of the GRADE methodology. The guidelines covered the following topics: i) Management of diverticulosis; ii) Symptomatic uncomplicated diverticular disease: diagnosis and treatment; iii) Acute diverticulitis: diagnosis and treatment; iv) Management of diverticular disease complications; v) Prevention of recurrent acute diverticulitis; vi) Interventional management of diverticular disease.

Address: Department of Medical-Surgical Sciences and Translational Medicine, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy. Electronic address: [email protected].; Gastroenterology and Endoscopy Unit, "Sant'Anna e San Sebastiano" Hospital Caserta, 81100 Caserta, Italy.; General Surgery Hospital of Imperia, Italy.; Department of Technical-Health Care Professions Dietetics Unit- AUSL Toscana Centro Santa Maria Nuova Hospital, Italy.; General Surgery, Biomedical Institute, Genoa, Italy.; Gastroenterology and Digestive Endoscopy San Martino Hospital, Belluno, Italy.; The Bridge Med, Milano, Italy.; Gastroenterology and Digestive Endoscopy, Avellino, Italy.; UOS Diagnostic and Interventional Digestive Endoscopy AOU Policlinico P.Giaccone, Palermo, Italy.; Gastroenterology and Digestive Endoscopy San Paolo Hospital, Bari, Italy.; Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.; Department of Medical-Surgical Sciences and Translational Medicine, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy.

DOI: 10.1016/j.dld.2024.06.031

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MeSH Terms: Humans, Diverticulosis, Colonic, Italy, Diverticulitis, Colonic, Diverticular Diseases, Recurrence