COVID-19-Associated Cerebellitis: A Case Report and Rehabilitation Outcome.

Danilo Donati, Roberto Tedeschi, Vincenza Amoruso, Valentina Boetto, Davide Glorioso, Lucia D'Auria

Journal: Cerebellum (London, England) 2024;23(6):2629-2637

PMID: 39008228

Abstract

INTRODUCTION

The COVID-19 pandemic has brought attention to neurological complications, including cerebellitis, characterized by inflammation of the cerebellum. Despite its rare occurrence, cerebellitis has been associated with COVID-19 infection, albeit the pathogenic mechanisms remain unclear.

CASE REPORT

We present the case of a 22-year-old male with acute onset ataxia and dysarthria during a SARS-CoV-2 infection. Diagnostic evaluations ruled out other causes, confirming cerebellitis. Treatment included steroid therapy, vitamin supplementation, physiotherapy, and intravenous immunoglobulins. Rehabilitation focused on enhancing balance, coordination, and daily activities. The patient showed significant improvement in functional abilities, with increased autonomy in daily activities and improved ambulation. Despite persistent mild symptoms, the multidisciplinary rehabilitation approach led to remarkable progress.

CONCLUSIONS

This case underscores the importance of recognizing and managing neurological complications, such as cerebellitis, in COVID-19 patients. A comprehensive approach combining medical treatment and rehabilitation is essential for optimizing outcomes. Further research is needed to elucidate the pathogenesis and optimal management strategies for such complications.

© 2024. The Author(s).

Address: Department of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum, University of Bologna, Via Zamboni 33, Bologna, 40126, Italy. [email protected].; Department of Geriatrics and Orthopaedics, Università Cattolica del Sacro Cuore, Rome, 00168, Italy.; Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, 27100, Italy.; Neuro-Orthopedic Unit, Sol et Salus Hospital, Rimini, 47922, Italy.; Physical Therapy and Rehabilitation Unit, Policlinico di Modena, Modena, 41125, Italy.; Physical Therapy and Rehabilitation Unit, Policlinico di Modena, Modena, 41125, Italy.; Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Largo del Pozzo 71, Modena, 41124, Italy.
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