Monitoring SpO: The Basics of Retinopathy of Prematurity (Back to Basics) and Targeting Oxygen Saturation.

Augusto Sola, María Teresa Montes Bueno, Cristian Emanuel Muñoz

Journal: Critical care nursing clinics of North America 2024;36(1):69-98

PMID: 38296377

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Abstract

Oxygen (O2) is a drug frequently used in newborn care. Adverse effects of hypoxia are well known but the damaging effects of excess oxygen administration and oxidative stress have only been studied in the last 2 decades. Many negative effects have been described, including retinopathy of prematurity . Noninvasive pulse oximetry (SpO2) is useful to detect hypoxemia but requires careful evaluation and understanding of the frequently changing relationship between O2 and hemoglobin to prevent hyperoxemia. Intention to treat SpO2 ranges should be individualized for every newborn receiving supplemental O2, according to gestational age, post-natal age, and clinical condition.

Address: Iberoamerican Society of Neonatology (SIBEN), 2244 Newbury Drive, Wellington, FL 3341, USA. Electronic address: [email protected].; Cardinal Glennon Children's Hospital, 1465 South Grand Avenue, St. Louis, MO 63104, USA.; Iberoamerican Society of Neonatology (SIBEN), Calle Villa de Marín n 37-1D, Madrid 28029, Spain.; Iberoamerican Society of Neonatology (SIBEN), Belgrano 378 -D8, San Luis, Argentina.

DOI: 10.1016/j.cnc.2023.08.004

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MeSH Terms: Infant, Newborn, Humans, Oxygen Saturation, Retinopathy of Prematurity, Infant, Premature, Oxygen, Oximetry, Hypoxia