Protective alleles and precision healthcare in crewed spaceflight.

Address: Transborder Medical Research Center, University of Tsukuba, Ibaraki, 305-8575, Japan.; Department of Genome Biology, Institute of Medicine, University of Tsukuba, Ibaraki, 305-8575, Japan.; School of Chemistry, University of Glasgow, Glasgow, G12 8QQ, UK.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, 10065, USA.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, 10021, USA.; The WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY, 10065, USA.; School of Medicine, University of Nottingham, Nottingham, DE22 3DT, UK.; School of Medicine, University of Nottingham, Nottingham, DE22 3DT, UK.; Ohio Musculoskeletal and Neurological Institute (OMNI), Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, 45701, USA.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, 10065, USA.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, 10021, USA.; Transborder Medical Research Center, University of Tsukuba, Ibaraki, 305-8575, Japan.; Department of Genome Biology, Institute of Medicine, University of Tsukuba, Ibaraki, 305-8575, Japan.; Colossal Biosciences, 1401 Lavaca St, Unit #155 Austin, Austin, TX, 78701, USA.; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; NGS Competence Center Tübingen (NCCT), University of Tübingen, Tübingen, Germany.; Yuri GmbH, Meckenbeuren, Germany.; Embry-Riddle Aeronautical University, Department of Human Factors and Behavioral Neurobiology, Daytona Beach, FL, 32114, USA.; Sovaris Aerospace, Boulder, CO, 80302, USA. [email protected].; Advanced Pattern Analysis & Human Performance Group, Boulder, CO, 80302, USA. [email protected].; GC Therapeutics Inc, Cambridge, MA, 02139, USA. [email protected].; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA. [email protected].; Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, MA, 02115, USA. [email protected].; SciLifeLab, KTH Royal Institute of Technology, Stockholm, 17165, Sweden. [email protected].; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, 10065, USA. [email protected].; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, 10021, USA. [email protected].; The WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY, 10065, USA. [email protected].; Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, MA, 02115, USA. [email protected].; The Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, 10065, USA. [email protected].