Resistance training improves cardiac function in older women: a randomized controlled trial.

Ricardo J Rodrigues, João P Nunes, Lauro C Vianna, Rodrigo R Fernandes, Paulo S Junior, Danilo S Bocalini, Luís B Sardinha, Edilson S Cyrino, Andrei C Sposito, Paolo M Cunha, Max D Oliveira, Patrícia C Brum, Luis C Miguita Junior, Elaine Batistella

Journal: GeroScience 2025;47(3):3461-3473

PMID: 39215795

Abstract

This investigation aimed to determine the effects of 24 weeks of resistance training (RT) on cardiac function in older women. Seventy-three physically independent older women were selected for this investigation. Participants were randomized into a training group (TG, n = 38) and a control group (CG, n = 35). The RT program was conducted over 24 weeks and consisted of three sessions a week. Participants performed eight exercises for the whole body in three sets of 8-12 repetitions. Tissue Doppler echocardiography was performed, according to current guidelines, before and after 24 weeks of the intervention. One-repetition maximum (1-RM) tests were used to assess muscular strength. A group vs. time interaction (P < 0.05) was shown for left ventricular end-diastolic volume (TG =  - 8.3% vs. CG =  - 0.6%), left ventricular end-systolic volume (TG =  - 10.6% vs. CG =  + 1.1%), and left atrial volume index (TG =  - 9.1% vs. CG =  + 3.9%). A main time effect (P < 0.05) was found for left ventricular mass index (TG =  + 4.9% vs. CG =  - 0.6%), septal thickness (TG =  + 3.3% vs. CG =  - 1.7%), left ventricular ejection fraction (TG =  + 3.7% vs. CG =  - 0.5%), E'/E septal (TG =  - 4.8% vs. CG =  + 0.5%), deceleration time (TG =  - 4.1% vs. CG =  + 3.9%), E septal (TG =  + 4.6% vs. CG =  - 0.6%), and E lateral (TG =  + 5.2% vs. CG =  - 1.1%). These results suggest that 24 weeks of RT improves cardiac morphological and functional variables in older women.

© 2024. The Author(s), under exclusive licence to American Aging Association.

Address: Nutrition, and Exercise Laboratory, Londrina State University, Londrina, Brazil.; Center of Heart, Londrina, Brazil.; Nutrition, and Exercise Laboratory, Londrina State University, Londrina, Brazil. [email protected].; Hospital Israelita Albert Einstein, São Paulo, Brazil. [email protected].; Nutrition, and Exercise Laboratory, Londrina State University, Londrina, Brazil.; Edith Cowan University, Joondalup, Australia.; Faculty of Physical Education, University of Brasília, Brasilia, DF, Brazil.; Cellular Molecular Exercise Physiology Laboratory, School of Physical Education and Sport, University of São Paulo, São Paulo, Brazil.; Experimental Physiology and Biochemistry Laboratory, Center of Physical Education and Sport, Federal University of Espírito Santo, Vitoria, Espirito Santo, Brazil.; Laboratory of Atherosclerosis and Vascular Biology, University of Campinas (Unicamp), Clinics Hospital, Unicamp, Cardiology Division, CampinasCampinas, São Paulo, Brazil.; Center of Heart, Londrina, Brazil.; Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, SP, Brazil.; Nutrition, and Exercise Laboratory, Londrina State University, Londrina, Brazil.; Exercise and Health Laboratory (CIPER), Faculdade de Motricidade Humana, Universidade de Lisboa, Lisboa, Portugal.

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