Cryptosporidium-induced acute kidney injury in the setting of acquired immunodeficiency syndrome.

Yi-Hsin Chou, Hung-Ju Fan

Journal: The American journal of the medical sciences 2024;368(3):253-257

PMID: 38795967

Abstract

Cryptosporidium is a pathogen that can cause infectious enteritis especially in immunocompromised patients. Acute kidney injury, electrolyte imbalance, and acid-base disorders may occur as a result of high volumes of intestinal fluid loss, which has not been previously reported to be a common manifestation of cryptosporidiosis. Numerous antigen detection methods can be used to ensure early diagnosis of Cryptosporidium infection, which is crucial to prevent morbidities. We report a unique case of cryptosporidiosis in a 33-year-old male patient with acute kidney injury and profound hypokalemia, hyponatremia, hypocalcemia, hypophosphatemia, hypomagnesemia, and metabolic acidosis. Following the initiation of antiretroviral therapy to human immunodeficiency virus, the patient's symptoms improved and he recovered fully from kidney injury and electrolyte imbalance, highlighting the importance of early antiretroviral therapy.

Copyright © 2024 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.

Address: Division of Nephrology, Taipei City Hospital Zhongxing Branch, Taiwan; School of Medicine, National Yang Ming Chiao Tung University, Taiwan. Electronic address: [email protected].; Department of Nursing, Taipei City Hospital Zhongxing Branch, Taiwan.
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