The role of registries in hematological disorders.

Sebastian Galeano, Daniel Neumann, Nada Hamad, Amado Karduss, Alaa M Elhaddad, Nosa G Bazuaye, Rafael de la Camara, Naeem A Chaudhri, Cinthya Correa, Cristobal Frutos, Fabio Ciceri, Gregorio Jaimovich, Mickey Bc Koh, Kaiyan Liu, Gayathri Nair, Jacob Passweg, Kristjan Paulson, Adriana Seber, Nina Worel, Yoshihisa Kodera, Anna Sureda, Per Ljungman, Damiano Rondelli, Alok Srivastava, Shinichiro Okamoto, Yoshiko Atsuta, Marcelo C Pasquini, Helen Baldomero, Minako Iida, Donal P McLornan, John A Snowden, Mahmoud Aljurf, Carmem Bonfim, Dietger Niederwieser, Laurent Garderet, Raffaella Greco, Wael Saber, Annalisa Ruggeri

Journal: Best practice & research. Clinical haematology 2024;37(2):101556

PMID: 39098798

Abstract

Hematopoietic cell transplantation (HCT) was developed more than 65 years ago to treat malignant blood disorders and irreversible bone marrow failures, with the aim of replacing a diseased hematopoietic system with a healthy one (allogeneic HCT). Decades later, the procedure was adapted to apply maximal chemotherapy or radiotherapy, which would result in bone marrow failure, but could be remedied by an infusion of a patient's own cryopreserved bone marrow (autologous HCT). Both treatments are high-risk and complex, especially during the initial phases. However, concerted efforts, vision, and collaboration between physicians and centers worldwide have resulted in HCT becoming a standard of care for many hematological disorders with progressive improvements in outcomes. Registries and the collaboration of societies worldwide have enabled the delivery of this curative therapy to many patients with fatal hematological diseases. More than 1.5 million HCT were performed between 1957 and 2019, and activity is continuously increasing worldwide.

Copyright © 2024. Published by Elsevier Ltd.

Address: Worldwide Network of Blood and Marrow Transplantation (WBMT) Transplant Activity Survey Office, University Hospital, Basel, CH, UK.; Institute of Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.; Haematology Clinical Research Unit, St. Vincent's Health Network, Kinghorn Cancer Centre, Sydney, Australia; Department of Haematology, St Vincent's Hospital Sydney, Australia; School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Australia; School of Medicine, Sydney, Australia; University of Notre Dame Australia, Australia.; Japanese Data Center for Hematopoietic Cell Transplantation, Nagakute, Japan; Department of Registry Science for Transplant and Cellular Therapy, Aichi Medical University School of Medicine, Nagakute, Japan.; Clinical Hematology Department, Institut Català d'Oncologia - L'Hospitalet, IDIBELL, Universitat de Barcelona, Barcelona, Spain.; Department of Promotion for Blood and Marrow Transplantation, Aichi Medical University School of Medicine, Nagakute, Japan.; Instituto de Cancerología-Clínica Las Américas, Medellín, Colombia.; Department of Pediatric Oncology and Stem Cell Transplantation Unit, Cairo University Cairo, Egypt.; Department of Hematology and Blood Transfusion, University of Benin Teaching Hospital, Edo State, Nigeria.; Pele Pequeno Principe Research Institute/ Pediatric Blood and Marrow Transplantation Program Hospital Pequeno Principe, Curitiba, Brazil.; Hematology Department, Hospital de la Princesa, Madrid, Spain.; Oncology Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.; Ospedale San Raffaele s.r.l., Haematology and BMT, Milano, Italy.; Hospital Israelita Albert Einstein, Sao Paula Brazil.; Instituto de Previsión Social, Asunción, Paraguay.; Hospital Británico, Montevideo, Uruguay.; Sorbonne Université, Service d'Hématologie et Thérapie Cellulaire, HôpitalPitié Salpêtrière, AP-HP, Paris, France.; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy.; Hospital Universitario Fundacion Favaloro, Buenos Aires, Argentina.; Institute for Infection and Immunity St. George's Hospital and Medical School, University of London, London, UK.; Department of Hematology, Peking University Institute of Hematology, Beijing, China.; Department of Cellular Therapy and Allogeneic Stem Cell Transplantation, Karolinska Comprehensive Cancer Center, Karolinska University Hospital Huddinge, Stockholm, Sweden.; Department of Haematology, University College Hospital, London, UK.; Blutspende SRK Schweiz AG, UK.; Division of Hematology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.; Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, WI, USA.; The Worldwide Network of Blood and Marrow Transplantation (WBMT) Transplant Activity Survey Office, University Hospital, Basel, Switzerland.; Section of Haematology/Oncology, Department of Internal Medicine, Max Rady College of Medicine, The University of Manitoba, Winnipeg, Manitoba, Canada.; Hospital Samaritano Higienópolis & Graacc-- Universidade Federal de Sao Paulo, Sao Paulo, Brazil.; Department of Haematology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.; Department of Hematology, Christian Medical College Hospital, Vellore, India.; Department of Transfusion Medicine and Cell Therapy, Medical University of Vienna, Vienna, Austria.; Division of Hematology/Oncology, University of Illinois at Chicago, Chicago, IL, USA.; University of Leipzig, Leipzig, Germany; Aichi Medical University School of Medicine, Nagakute, Japan; Lithuanian University of Health Sciences, Kaunas, Lithuania. Electronic address: [email protected].
Bant logo

© Copyright 2026, Nutrition Evidence

NED wishes to thank the following organisations for their support:

We use cookies to improve your experience and analyze site traffic with Google Analytics. By continuing to use our site, you agree to our use of cookies. Learn more.