Reply: Spatial and temporal manipulation of the Scn1a gene affect adult brain function.

Vania Broccoli, Claudia Di Berardino, Martina Mainardi, Simone Brusco, Elena Benvenuto, Gaia Colasante

Journal: Brain : a journal of neurology 2024;147(4):e31-e33

PMID: 38099567

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Abstract

Address: Stem Cell and Neurogenesis Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.; Stem Cell and Neurogenesis Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.; Neuroscience and Experimental Neurology PhD Program, Vita-Salute San Raffaele University, 20132 Milan, Italy.; Stem Cell and Neurogenesis Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.; Institute of Neuroscience, National Research Council (CNR), 20129 Milan, Italy.; Stem Cell and Neurogenesis Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.; Gene and Cell Therapy PhD Program, Vita-Salute San Raffaele University, 20132 Milan, Italy.

DOI: 10.1093/brain/awad423

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MeSH Terms: Adult, Humans, Epilepsy, Temporal Lobe, NAV1.1 Voltage-Gated Sodium Channel, Nervous System Physiological Phenomena, Brain