The Extraction, Determination, and Bioactivity of Curcumenol: A Comprehensive Review.

Guohua Li, Xinbing Sui, Qibiao Wu, Jie Li, Yitian Sun, Chunsong Cheng

Journal: Molecules (Basel, Switzerland) 2024;29(3):

PMID: 38338400

Abstract

is a member of the (zedoary, Zingiberaceae) family, which has a long history in traditional Chinese medicine (TCM) due to its abundant biologically active constituents. Curcumenol, a component of , has several biological activities. At present, despite different pharmacological activities being reported, the clinical usage of curcumenol remains under investigation. To further determine the characteristics of curcumenol, the extraction, determination, and bioactivity of the compound are summarized in this review. Existing research has reported that curcumenol exerts different pharmacological effects in regard to a variety of diseases, including anti-inflammatory, anti-oxidant, anti-bactericidal, anti-diabetic, and anti-cancer activity, and also ameliorates osteoporosis. This review of curcumenol provides a theoretical basis for further research and clinical applications.

Address: State Key Laboratory of Quality Research in Chinese Medicines, Faculty of Chinese Medicine, Macau University of Science and Technology, Macau 999078, China.; College of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.; School of Environmental and Chemical Engineering, Zhaoqing University, Zhaoqing 526061, China.; State Key Laboratory of Quality Research in Chinese Medicines, Faculty of Chinese Medicine, Macau University of Science and Technology, Macau 999078, China.; College of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.; Lushan Botanical Garden, Chinese Academy of Sciences, Jiujiang 332900, China.; College of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.; State Key Laboratory of Quality Research in Chinese Medicines, Faculty of Chinese Medicine, Macau University of Science and Technology, Macau 999078, China.; Zhuhai M.U.S.T. Science and Technology Research Institute, Zhuhai 519031, China.; Guangdong-Hong Kong-Macao Joint Laboratory for Contaminants Exposure and Health, Guangzhou 510006, China.

DOI: 10.3390/molecules29030656

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MeSH Terms: Sesquiterpenes, Curcuma