Ultra-processed Food and Obesity: What Is the Evidence?

Samuel J Dicken, Rachel L Batterham

Journal: Current nutrition reports 2024;13(1):23-38

PMID: 38294671

Abstract

PURPOSE OF REVIEW

Obesity is a growing global healthcare concern. A proposed driver is the recent increase in ultra-processed food (UPF) intake. However, disagreement surrounds the concept of UPF, the strength of evidence, and suggested mechanisms. Therefore, this review aimed to critically appraise the evidence on UPF and obesity.

RECENT FINDINGS

Observational studies demonstrate positive associations between UPF intake, weight gain, and overweight/obesity, more clearly in adults than children/adolescents. This is supported by high-quality clinical data. Several mechanisms are proposed, but current understanding is inconclusive. Greater UPF consumption has been a key driver of obesity. There is a need to change the obesogenic environment to support individuals to reduce their UPF intake. The UPF concept is a novel approach that is not explained with existing nutrient- and food-based frameworks. Critical analysis of methodologies provides confidence, but future observational and experimental research outputs with greater methodological rigor will strengthen findings, which are outlined.

© 2024. The Author(s).

Address: Centre for Obesity Research, Department of Medicine, University College London (UCL), London, WC1E 6JF, UK.; Centre for Obesity Research, Department of Medicine, University College London (UCL), London, WC1E 6JF, UK. [email protected].; Bariatric Centre for Weight Management and Metabolic Surgery, University College London Hospital (UCLH), London, NW1 2BU, UK. [email protected].; National Institute for Health Research, Biomedical Research Centre, University College London Hospital (UCLH), London, W1T 7DN, UK. [email protected].
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