A catalog of ethanol-producing microbes in humans.

Maryam Tidjani Alou, Jean-Charles Dufour, Matthieu Million, Babacar Mbaye, Reham Magdy Wasfy, Patrick Borentain, Rene Gerolami

Journal: Future microbiology 2024;19(8):697-714

PMID: 38700288

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Abstract

Endogenous ethanol production emerges as a mechanism of nonalcoholic steatohepatitis, obesity, diabetes and auto-brewery syndrome. To identify ethanol-producing microbes in humans, we used the NCBI taxonomy browser and the PubMed database with an automatic query and manual verification. 85 ethanol-producing microbes in human were identified. , and were the most represented fungi. Enterobacteriaceae was the most represented bacterial family with mainly and . Species of the Lachnospiraceae and Clostridiaceae family, of the Lactobacillales order and of the genus were also identified. This catalog will help the study of ethanol-producing microbes in human in the pathophysiology, diagnosis, prevention and management of human diseases associated with endogenous ethanol production.

Address: Aix Marseille Université, AP-HM, MEPHI, Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.; Department of Hepatology, La Timone University Hospital, AP-HM, Marseille, France.; Aix Marseille Université, AP-HM, MEPHI, Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.; Department of Hepatology, La Timone University Hospital, AP-HM, Marseille, France.; INSERM, IRD, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l'Information Médicale, ISSPAM, Aix Marseille University, 13385 Marseille, France.; APHM, Hôpital de la Timone, Service Biostatistique et Technologies de l'Information et de la Communication, 13385 Marseille, France.

DOI: 10.2217/fmb-2023-0250