Emerging role of calprotectin in gastroenterology.

Andrew Poullis, Russell Foster, Michael A Mendall, Magne K Fagerhol

Journal: Journal of gastroenterology and hepatology 2003;18(7):756-62

PMID: 12795745

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Abstract

Calprotectin is a calcium and zinc binding protein of the S100 family derived predominantly from neutrophils and monocytes. It is detectable in body fluids and tissue samples and is emerging as a valuable marker in the diagnosis, and the monitoring and determining of the prognosis of commonly encountered gastroenterological conditions. Fecal calprotectin, in particular, has for a long time been regarded as a promising marker of gastrointestinal pathology and has now been established as a routine test in Norway and at several centers in the UK.

Address: Gastroenterology, Endocrinology and Metabolism Division, St George's Hospital Medical School, London and Mayday University Hospital, Surrey, UK. [email protected]

DOI: 10.1046/j.1440-1746.2003.03014.x

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MeSH Terms: Biomarkers, Gastrointestinal Diseases, Humans, Leukocyte L1 Antigen Complex, Zinc