Evaluation of the Role of Potassium Channels in the Proliferation, Migration, and Invasion of Blood Cells.

Valeria Y Vasileva, Vladislav I Chubinskiy-Nadezhdin

Journal: Methods in molecular biology (Clifton, N.J.) 2024;2796():185-190

PMID: 38856902

Abstract

The potassium channels are one of the key regulators of cell membrane potential and permeability properties of blood cells. The changes in functioning of potassium channels control crucial cell processes such as proliferation, viability, migration, and invasion. The correct estimation of these processes is important for the characterization of physiological and pathophysiological cell states. Here, we present the experimental protocol for evaluation of the role of potassium ion channels in the proliferation, migration, and invasion of blood cells.

Address: Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russian Federation.; Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russian Federation. [email protected].

DOI: 10.1007/978-1-0716-3818-7_11

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https://doi.org/10.1007/978-1-0716-3818-7_11

MeSH Terms: Cell Movement, Cell Proliferation, Humans, Potassium Channels, Blood Cells, Membrane Potentials