Distribution and roles of Ligilactobacillus murinus in hosts.

Wenfeng Zhang, Chan Wu, Yuting Wu, Han Shen, Jiawen Li, Song Liu, Fenglin Wu, Hongwei Shao, Zhou Chuandong, Jicong Hu, Guanxi Lai, Changli Tao

Journal: Microbiological research 2024;282():127648

PMID: 38367479

Abstract

Ligilactobacillus murinus, a member of the Ligilactobacillus genus, holds significant potential as a probiotic. While research on Ligilactobacillus murinus has been relatively limited compared to well-studied probiotic lactic acid bacteria such as Limosilactobacillus reuteri and Lactobacillus gasseri, a mounting body of evidence highlights its extensive involvement in host intestinal metabolism and immune activities. Moreover, its abundance exhibits a close correlation with intestinal health. Notably, beyond the intestinal context, Ligilactobacillus murinus is gaining recognition for its contributions to metabolism and regulation in the oral cavity, lungs, and vagina. As such, Ligilactobacillus murinus emerges as a potential probiotic candidate with a pivotal role in supporting host well-being. This review delves into studies elucidating the multifaceted roles of Ligilactobacillus murinus. It also examines its medicinal potential and associated challenges, underscoring the imperative to delve deeper into unraveling the mechanisms of its actions and exploring its health applications.

Copyright © 2024 Elsevier GmbH. All rights reserved.

Address: School of Life Science and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, Guangdong, PR China.; School of Clinical Medicine, Guangdong Pharmaceutical University, Guangzhou, Guangdong, PR China.; School of Clinical Pharmacy, Guangdong Pharmaceutical University, Guangzhou, Guangdong, PR China.; School of Life Science and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, Guangdong, PR China. Electronic address: [email protected].; School of Life Science and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, Guangdong, PR China. Electronic address: [email protected].
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