A primer on the use of machine learning to distil knowledge from data in biological psychiatry.

Address: Applied Artificial Intelligence Institute (A2I2), Burwood, VIC, 3125, Australia.; Department of Psychiatry and Behavioral Sciences, Norton College of Medicine at SUNY Upstate Medical University, Syracuse, NY, 13210, USA.; Institute of Medical Science, University of Toronto, Toronto, ON, M5S 1A1, Canada.; Pharmacogenetics Research Clinic, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, M5S 1A1, Canada.; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, 2308, Australia.; Precision Medicine Research Program, Hunter Medical Research Institute, Newcastle, NSW, 2308, Australia.; Department of Medical Informatics, Medical University Center Göttingen, Göttingen, Lower Saxony, 37075, Germany.; Hospital Zurich, University of Zurich, Zurich, 8091, Switzerland.; Department of Rheumatology and Immunology, University Hospital Bern, Bern, 3010, Switzerland.; Department for Biomedical Research (DBMR), University of Bern, Bern, 3010, Switzerland.; Pharmacogenetics Research Clinic, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, M5S 1A1, Canada.; Pharmacogenetics Research Clinic, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, M5S 1A1, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, M5S 1A1, Canada.; Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Baden-Württemberg, J5 68159, Germany.; Department Human Genetics, McGill University Health Centre, Montreal, QC, H4A 3J1, Canada.; Psychiatry, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Neuroscience and Physiology, Norton College of Medicine at SUNY Upstate Medical University, Syracuse, NY, 13210, USA.; Department of Business Administration, Gies College of Business, University of Illinois at Urbana-Champaign, Champaign, IL, 61820, USA.; Department of Biomedical and Translational Sciences, Carle-Illinois School of Medicine, University of Illinois at Urbana-Champaign, Champaign, IL, 61820, USA.; Department of Psychiatry and Behavioral Sciences, Norton College of Medicine at SUNY Upstate Medical University, Syracuse, NY, 13210, USA.; Department of Neuroscience and Physiology, Norton College of Medicine at SUNY Upstate Medical University, Syracuse, NY, 13210, USA.; Electrical Engineering and Computer Science, Syracuse University, Syracuse, NY, 13244, USA.; Discipline of Psychiatry and Mental Health, University of New South Wales, Sydney, NSW, 2052, Australia.; Mental Health Research Unit, South Western Sydney Local Health District, Liverpool, NSW, 2170, Australia.; Usher Institute, University of Edinburgh, Edinburgh, EH8 9YL, UK.; Clinical Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Baden-Württemberg, J5 68159, Germany.; Biomedical and Health Informatics/Computer Science Department, State University of New York at Oswego, Oswego, NY, 13126, USA.; Intelligent Bio Systems Lab, State University of New York at Oswego, Oswego, NY, 13126, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Pharmacogenetics Research Clinic, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, M5S 1A1, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON, M5S 1A1, Canada.; Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital of Würzburg, Würzburg, 97080, Germany.; Department of Psychiatry and Behavioral Sciences, Norton College of Medicine at SUNY Upstate Medical University, Syracuse, NY, 13210, USA. [email protected].; Department of Neuroscience and Physiology, Norton College of Medicine at SUNY Upstate Medical University, Syracuse, NY, 13210, USA. [email protected].; Department of Public Health and Preventive Medicine, Norton College of Medicine at SUNY Upstate Medical University, Syracuse, NY, 13210, USA. [email protected].