Recent advances in electrochemical cell-based biosensors for food analysis: Strategies for sensor construction.

Shipeng Gao, Lidan Niu, Zhihua Li, Xiaobo Zou, Di Zhang, Seeram Ramakrishna, Xiaoou Wei, Vundrala Sumedha Reddy, Xiaodong Zhai, Jiyong Shi

Journal: Biosensors & bioelectronics 2024;248():115947

PMID: 38181518

Full Text on Elsevier Science View on PubMed

Abstract

Owing to their advantages such as great specificity, sensitivity, rapidity, and possibility of noninvasive and real-time monitoring, electrochemical cell-based biosensors (ECBBs) have been a powerful tool for food analysis encompassing the areas of nutrition, flavor, and safety. Notably, the distinctive biological relevance of ECBBs enables them to mimic physiological environments and reflect cellular behaviors, leading to valuable insights into the biological function of target components in food. Compared with previous reviews, this review fills the current gap in the narrative of ECBB construction strategies. The review commences by providing an overview of the materials and configuration of ECBBs, including cell types, cell immobilization strategies, electrode modification materials, and electrochemical sensing types. Subsequently, a detailed discussion is presented on the fabrication strategies of ECBBs in food analysis applications, which are categorized based on distinct signal sources. Lastly, we summarize the merits, drawbacks, and application scope of these diverse strategies, and discuss the current challenges and future perspectives of ECBBs. Consequently, this review provides guidance for the design of ECBBs with specific functions and promotes the application of ECBBs in food analysis.

Address: School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, PR China; Department of Mechanical Engineering, National University of Singapore, Singapore 117575, Singapore.; Department of Mechanical Engineering, National University of Singapore, Singapore 117575, Singapore.; School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, PR China.; Key Laboratory of Condiment Supervision Technology for State Market Regulation, Chongqing Institute for Food and Drug Control, Chongqing 401121, PR China.; School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, PR China; Key Laboratory of Condiment Supervision Technology for State Market Regulation, Chongqing Institute for Food and Drug Control, Chongqing 401121, PR China. Electronic address: [email protected].; Department of Mechanical Engineering, National University of Singapore, Singapore 117575, Singapore. Electronic address: [email protected].; School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, PR China. Electronic address: [email protected].

DOI: 10.1016/j.bios.2023.115947

Link outs

Free resources

Miscellaneous:

https://assays.cancer.gov/CPTAC-1548

Subscription / membership required

Full Text Sources:

https://linkinghub.elsevier.com/retrieve/pii/S0956...

MeSH Terms: Biosensing Techniques, Electrochemical Techniques, Electrodes, Food Analysis