Living Donor Intestinal Transplantation.

Alessandro Martinino, Enrico Benedetti, Pierpaolo Di Cocco, Federico Pinto, Benito Valdepenas, Mario Spaggiari, Ivo Tzvetanov

Journal: Gastroenterology clinics of North America 2024;53(3):441-452

PMID: 39068005

Full Text on Elsevier Science View on PubMed

Abstract

This study explores intestinal transplantation (ITx) as a viable treatment option for intestinal failure (IF). Historical development, donor and recipient considerations, surgical techniques, immunosuppression, and outcomes, are reviewed with particular emphasis to the value of living donor ITx. The review highlights the evolution of ITx and emphasizes the ongoing need for patient-specific selection processes. In the realm of pediatric ITx, the article underlines the significance of early intervention to mitigate IF-related liver disease. Overall, it provides a comprehensive overview of this life-saving procedure.

Address: Division of Transplantation, Department of Surgery, University of Illinois at Chicago, Chicago, IL, USA.; Division of Transplantation, Department of Surgery, University of Illinois at Chicago, Chicago, IL, USA. Electronic address: [email protected].; Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA.

DOI: 10.1016/j.gtc.2023.12.005