Federica Conti, Chiara Bianca Maria Platania, Francesca Lazzara, Filippo Drago, Claudio Bucolo, Erika Giuffrida, Chiara Maria Eandi
Journal: Current opinion in pharmacology 2024;74():102425
PMID: 38183849
With the spread of the "omics" sciences, the approaches of systems biology can be considered as new paradigms of pharmacological research for discovery of novel targets and/or treatments for complex multifactorial diseases. Data from omics sciences can be used for the design of biologic networks, that in turn can be quantitatively analyzed to identify new pharmacological targets. In this review, we will introduce the concept of network pharmacology, particularly the application of this innovative approach in the field of ocular pharmacology, with a focus on retinal diseases such as diabetic retinopathy (DR), age-related macular degeneration (AMD) and glaucoma.
Copyright © 2023 The Author(s). Published by Elsevier Ltd.. All rights reserved.
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