Strains and Their Metabolites for Biocontrol of Phytopathogens in Agriculture.

Sustainable agriculture is increasingly linked to biological pesticides as alternatives to agro-chemicals. species suppress plant diseases through their unique traits and numerous metabolites. Although many strains have been developed into commercial products, their roles in the biocontrol of phytopathogens and mechanisms of functional metabolite synthesis remain poorly understood. In this review, biocontrol of plant diseases by is summarized on the basis of classification of fungal and bacterial diseases and secondary metabolites produced by that act on phytopathogenic microorganisms are discussed. The associated non-ribosomal peptide synthetases and polyketide synthetases responsible for biosynthesis of these secondary metabolites are also investigated, and advances in fermentation of are described. Finally, the need to develop precise and effective biocontrol methods for plant diseases is highlighted.