Precision medicine: "Point of Care Ultrasound" (PoCUS) in the diagnostic approach to the patient with hyponatremia.

Mara Serrano Soto, Roberto Alcázar Arroyo, Jaime Mazón Ruiz, Eduardo Josue Banegas, Jose Luis Pérez Canga, Luis Bravo González-Blas, Natalia Menéndez García, Adriana Cavada Bustamante, Emilio Sánchez Álvarez, Gregorio A Romero-González

Journal: Nefrologia 2024;44(2):159-164

PMID: 38631962

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Abstract

Hyponatremia is a multifactorial disorder defined as a decrease in plasma sodium concentration. Its differential diagnosis requires an adequate evaluation of the extracellular volume (ECV). However, ECV determination, simply based on the clinical history, vital signs, physical examination, and laboratory findings can leads to misdiagnosis and inappropriate treatment. The use of Point-of-Care Ultrasound (POCUS), through the combination of Lung Ultrasound (LUS), Venous Excess UltraSound (VExUS) and Focused Cardiac Ultrasound (FoCUS), allows a much more accurate holistic assessment of the patient's ECV status in combination with the other parameters.

Address: Servicio de Nefrología, Hospital Universitario Central de Asturias, Oviedo, Spain. Electronic address: [email protected].; Servicio de Nefrología, Hospital Universitario Central de Asturias, Oviedo, Spain.; Servicio de Nefrología, Hospital Universitario San Agustín, Avilés, Spain.; Servicio de Nefrología, Hospital Universitario Marqués de Valdecilla, Santander, Spain; International Renal Research Institute Vicenza, Vicenza, Italy.; Servicio de Nefrología, Hospital Universitario de Cabueñes, Gijón, Spain.; Servicio de Nefrología, Hospital Universitario Infanta Leonor, Madrid, Spain.; International Renal Research Institute Vicenza, Vicenza, Italy; Servicio de Nefrología, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.

DOI: 10.1016/j.nefroe.2024.03.022

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MeSH Terms: Humans, Hyponatremia, Ultrasonography, Point-of-Care Systems, Precision Medicine, Lung