Continuous Glucose Monitoring for Prediabetes: Roles, Evidence, and Gaps.

Cecilia C Low Wang, Rodolfo J Galindo, Viral N Shah, Halis K Akturk, Salwa J Zahalka

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2025;31(8):1054-1060

PMID: 40409607

Full Text on Elsevier Science View on PubMed

Abstract

Continuous glucose monitoring (CGM) has transformed the care of patients with diabetes, and there is great potential to extend these benefits to prediabetes. The recent US Food and Drug Administration approval of over-the-counter CGMs has increased interest for use in individuals with prediabetes. It is of particular interest to use CGM to guide early individualized lifestyle interventions to prevent the progression of prediabetes to diabetes and support reversion to normoglycemia. In this review, we discuss published evidence regarding CGM metrics in normoglycemia, briefly review the use of CGM to diagnose prediabetes, and review available evidence for CGM use during lifestyle interventions in individuals with prediabetes. Future studies are needed to validate CGM metrics for prediabetes and evaluate effects of early intervention with CGM in this population.

Address: Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Colorado Anschutz Medical Campus School of Medicine, Aurora, Colorado.; Barbara Davis Center for Diabetes, University of Colorado, Aurora, Colorado.; Division of Endocrinology, University of Miami Miller School of Medicine, Miami, Florida.; Division of Endocrinology & Metabolism, Indiana University School of Medicine, Indianapolis, Indiana.; Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Colorado Anschutz Medical Campus School of Medicine, Aurora, Colorado. Electronic address: [email protected].

DOI: 10.1016/j.eprac.2025.05.742

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MeSH Terms: Humans, Prediabetic State, Blood Glucose Self-Monitoring, Blood Glucose, Life Style, Continuous Glucose Monitoring