Expert Consensus on the Diagnosis and Management of Carotid Atherosclerotic Plaque: Pathophysiology, Clinical Management, and Preventive Approaches.

Rongjun Zou, Xiaoping Fan, Hongshuo Shi, Qingyong He, Hang Zhu, Xing Chang, Hao Zhou, Hui Zhang, Zhijiang Guo, Yingjie Tian, Qianying Hao, Qihui Zhang, Sang-Bing Ong

Journal: International journal of medical sciences 2025;22(11):2738-2756

PMID: 40520900

Abstract

To standardize and harmonize pharmacist-led cholesterol-lowering medication therapy management (MTM) for patients with carotid atherosclerosis and plaque, the Expert Consensus on Lipid-Lowering Pharmacotherapy Management in Patients with Carotid Atherosclerosis and Plaque was developed under the leadership of the PLA General Hospital. This consensus establishes a systematic framework spanning the full-cycle management process: data collection, analytical evaluation, intervention implementation, and long-term follow-up, supported by standardized protocols, documentation forms, and assessment tools. It prioritizes seven evidence-based evaluation domains: therapeutic efficacy, drug selection, dosing appropriateness, adverse reactions, drug-drug/food interactions, cost-effectiveness, and medication adherence. By integrating practical workflows with clinical decision-support tools, the consensus aims to optimize therapeutic outcomes, mitigate safety risks, and provide actionable guidance for healthcare professionals managing this high-risk population.

© The author(s).

Address: Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053.; The Sixth Medical Center of PLA General Hospital, Beijing, 100048.; Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203.; Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053.; Beijing University of Chinese Medicine, Beijing, 100029.; Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053.; Hubei University of Chinese Medicine, Hubei, Wuhan, 430065.; State Key Laboratory of Traditional Chinese Medicine Syndrome/Department of Cardiovascular Surgery, Guangdong Provincial Hospital of Chinese Medicine, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, the Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou 510120, Guangdong, China.; Dongfang Hospital, Beijing University of Chinese Medicine, 100078.
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