Diabetes Mellitus in Pregnancy: Implications for Obstetric Anesthesia.

Amir Moheet, W Kirke Rogers, Iryna Chugaieva, Sarah A Wernimont

Journal: Anesthesiology 2025;143(2):424-443

PMID: 40626748

Abstract

Diabetes in pregnancy is a common obstetric comorbidity that increases the risks of pregnancy-specific complications. The authors describe in this review how understanding ambulatory use of insulin can impact peripartum anesthesia care. Additionally, they describe the appropriate delivery, dosing, and timing of insulin during birth as relevant for anesthesiologists. They discuss the indications and limitations of technologies such as continuous glucose monitors and insulin pumps in pregnancy, and describe their relevance and appropriate management in the perioperative and peripartum period. Finally, the authors review the unique complication of euglycemic diabetic ketoacidosis and provide appropriate management strategies, as anesthesiologists may be in a position to recognize this complication that could otherwise be overlooked.

Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc., on behalf of the American Society of Anesthesiologists.

Address: Division of Critical Care Medicine, Department of Anesthesiology, University of Minnesota Medical School, Minneapolis, Minnesota.; Department of Anesthesiology, University of Minnesota Medical School, Minneapolis, Minnesota.; Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota.; Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology and Women's Health, University of Minnesota Medical School, Minneapolis, Minnesota.
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